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Products covered HS or CCCN where applicable, otherwise national tariff heading. ICS numbers may be provided in addition, where applicable ; : Drugs Title, number of pages and language s ; of the notified document: Partial amendment to the Minimum Requirements for Biological Products 1 page, in English ; . Description of content: The Minimum Requirements for Biological Products shall be partially amended to add the standard for a vaccine to be newly approved.
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Cerebellar development. Nature 221, 554-555. 15. Chase, H. P. 1973 ; The effects of in trauterine and postnatal undernutrition on normal brain development. Ann. N.Y. Acad. Sci. 205, 231-244. 16. Lapham, L. W. 1968 ; Tetraploid DNA content of Purkinje neurons of human cerebel lar cortex. Science 59, 310-312. 17. Winick, M. 1968 ; Changes in nucleic acid and protein content of the human brain dur ing growth. Pediatr. Res. 2, 352-355. 18. Dobbing, J. & Sands, J. 1973 ; Quantita tive growth and development of human brain. Arch. Dis. Child. 48, 757-767. 19. Jansen, G. R. 1969 ; Total protein value of protein- and amino acid-supplemented bread. Am. J. Clin. Nutr. 22, 38-43 and acebutolol.
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Egan, S.E., Giddings, B.W., Brooks, M.W., Buday, L., Sizeland, A.M., and Weinberg, R.A. 1993 ; . Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363, 4551. Fontenot, J.D., Mariappan, S.V.S., Catasti, P., Domenech, N., Finn, O.J., and Gupta, G. 1995 ; . Structure of a tumor associated antigen containing a tandemly repeated immunodominant epitope. J. Biomol. Struct. Dynam. 13, 245260. Gendler, S., Spicer, A.P., Lalani, E.-N., Duhig, T., Peat, N., Burchell, J., Pemberton, L., Boshell, M., and Taylor-Papadimitriou, J. 1991 ; . Structure and biology of a carcinoma-associated mucin, MUC1. Am. Rev. Respir. Dis. 144, S42S47. Gottardi, C.J., and Caplan, M.J. 1992 ; . Cell surface biotinylation in the determination of epithelial membrane polarity. J. Tissue Culture Methods 14, 173180. Hanisch, F.-G., Uhlenbruck, G., Peter-Katalinic, J., Egge, H., Dabrowski, J., and Dabrowski, U. 1989 ; . Structures of neutral O-linked polylactosaminoglycans on human skim milk mucins. J. Biol. Chem. 264, 872 883. Hansen, S.H., Sandvig, K., and van Deurs, B. 1993 ; . Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification. J. Cell Biol. 121, 6172. Hardy, S., Kitamura, M., Harris-Stansil, T., Dai, Y., and Phipps, M.L. 1997 ; . Construction of adenovirus vectors through Cre-lox recombination. J. Virol. 71, 18421849. Hilkens, J., Ligtenberg, M.J.L., Vox, H.L., and Litvinov, S.V. 1992 ; . Cell membrane-associated mucins and their adhesion-modulating property. Trends Biochem. Sci. 17, 359 363. Huang, K.M., and Snider, M.D. 1993 ; . Glycoprotein recycling to the galactosyltransferase compartment of the Golgi complex. J. Biol. Chem. 268, 93029310. Hull, S.R., Bright, A., Carraway, K.L., Abe, M., Hayes, D.F., and Kufe, D.W. 1989 ; . Oligosaccharide differences in the DF3 sialomucin antigen from normal human milk and the BT-20 human breast carcinoma cell line. Cancer Commun. 1, 261267. Hull, S.R., Sugarman, E.D., Spielman, J., and Carraway, K.L. 1991 ; . Biosynthetic maturation of an ascites tumor cell surface sialomucin. J. Biol. Chem. 266, 13580 13586. Kingsley, D.M., Kozarsky, K.F., Hobbie, L., and Krieger, M. 1986 ; . Reversible defects in O-linked glycosylation and LDL receptor expression in a UDP-Gal UDP-GalNAc 4-epimerase deficient mutant. Cell 44, 749 759. Kirchhausen, T., Bonifacino, J.S., and Riezman, H. 1997 ; . Linking cargo to vesicle formation: receptor tail interactions with coat proteins. Curr. Opin. Cell Biol. 9, 488 495. Kornfeld, S. 1987 ; . Trafficking of lysosomal enzymes. FASEB J. 1, 462 468. Kozarsky, K., Kingsley, D., and Krieger, M. 1988a ; . Use of a mutant cell line to study the kinetics and function of O-linked glycosylation of low density lipoprotein receptors. Proc. Natl. Acad. Sci. USA 85, 4335 4339. Kozarsky, K.F., Call, S.M., Dower, S.K., and Krieger, M. 1988b ; . Abnormal intracellular sorting of O-linked carbohydrate-deficient interleukin-2 receptors. Mol. Cell Biol. 8, 33573363. Laemmli, U.K. 1970 ; . Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680 685. Litvinov, S.V., and Hilkens, J. 1993 ; . The epithelial sialomucin, episialin, is sialylated during recycling. J. Biol. Chem. 268, 21364 21371. Lloyd, K.O., Burchell, J., Kudryashov, V., Yin, B.W.T., and TaylorPapadimitriou, J. 1996 ; . Comparison of O-linked carbohydrate and acidophilus.
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R ESULTS FOR A LCOHOLISM E XPERIMENTS . We ran the above test on the Wikipedia page about alcoholism [40], B, and a selected set, B , of 30 keywords from the medical term index [29]. For the run analyzed in Figure 4, the set B was selected by starting at the 52nd entry in the medical term index and selecting every 100th word until 30 were accumulated in order to approximate a random selection of medical terms. As expected, keyword pairs from input B generated far more hits for alcoholism 47.82% ; than B 9.43% ; . In addition, we manually re viewed the URLs that yielded a hit in v KAlc for a seemingly innocuous pair of keywords. These results are summarized in figure 4. A PPLYING THE R ESULTS . When redacting medical records, a redaction practitioner might use the results in figures 3 and 4 to choose content to redact. For example, figure 4 indicates the medications naltrexone and acamprosate should be removed due to their popularity as alcoholism treatments. The words identified as STD-inference enabling are far more ambiguous e.g and acitretin.
The numerator for both basic and diluted EPS is net earnings available to common shareholders. The denominator for basic EPS is the weighted-average number of common shares outstanding during the period. The following is a reconciliation of the shares denominator ; of the basic and diluted per-share computations.
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Background: Gynecological diseases are more common in HIV-infected women and in general they are more severe. Therefore it is recommended that all HIV-infected women should have a gynecological visit including a cervical smear at least once a year. Objectives: To analyze clinical, sociodemographic and care provider related factors that are associated with poor gynecological follow-up among HIVinfected women. Methods: Half-yearly prospective questionnaire submitted to women of the Swiss HIV Cohort Study SHCS ; between April 2001 and December 2004. At every follow-up visit, the women were asked if they had had a gynecological examination since the last visit. Longitudinal generalized estimating equations models were fit where the primary outcome was `gynecological visit' in a time period of 14 months. This time period was chosen since most study participants had had two follow-up visits within 14 months and one visit is not very informative if the patient indicates that she had no gynecological visit. Results: 2185 women were included in the analysis. 1425 women had at least two follow-up visits in every time period, of which 35.6% reported a gynecological visit in each time period and 8.0% reported that they had never consulted a gynecologist. Factors associated with a poor gynecological follow-up were: lower education odds ratio OR 0.74, p 0.01 ; , current intravenous drug use 1.53, p 0.01 ; , older age 1.02, p 0.01 ; , undetectable viral load 0.88, p 0.04 ; , and seeing a private infectiologist as care provider 0.81, p 0.02 ; , while ethnicity 1.04, p 0.48 ; and CD4 cell count 0.99, p 0.35 ; were not associated. Conclusions: A substantial number of HIV positive women from the SHCS have a bad 57% ; or even absent 8% ; gynecological follow-up. Due to higher incidence of gynecological diseases, follow-ups are very important and should be discussed regularly with HIV positive women and adalimumab
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| Acamprosate treatmentIs still in doubt after thorough history taking, examination, and investigations, ongoing observations and follow-up may ultimately delineate the disease entity. The use of a dopa challenge may aid diagnosis but remains controversial. From a local point of view, a recent registry detailing 1091 patients with PD in Hong Kong 21 showed that tremor was the most common presenting symptom 77.3% ; , followed by slowness 48.7% ; , and stiffness 37.8% ; . Slightly more patients initially presented with symptoms on the right side 47.5% ; , and the majority 75.9% ; were considered to have mild-to-moderate disease. As many as 22.9% of patients experienced falls, among whom 20.4% had fractures. It was also noted that women with PD were more likely to fall and to sustain fractures. The reason for the association between female sex and fall is unknown, although a propensity to fractures is known to be related to postmenopausal hormonal changes. For those with young-onset 50 years ; PD, in whom two family members including the proband ; are affected, referral to specialists for possible genetic testing can be considered, although it raises many issues for patients and their family.3 and adefovir.
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